James Van Der Beek sparks conversation as experts examine colorectal cancer and medical marijuana and how cannabis may help patients manage symptoms. James Van Der Beek just lost his battle to colorectal cancer, one of the most common cancers in the United States and worldwide. It begins in the colon or rectum, which are parts of the large intestine responsible for absorbing water and processing waste before it leaves the body. Most colorectal cancers start as small, noncancerous growths called polyps  develop on the inner lining of the colon or rectum. Over time, some of these polyps can become cancerous. It is a tough joinery, but what about colorectal cancer and medical marijuana?

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Risk factors for colorectal cancer include age, family history, certain genetic conditions, inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis, obesity, smoking, heavy alcohol use, and diets high in red or processed meats. Symptoms may include persistent changes in bowel habits, rectal bleeding, abdominal discomfort, unexplained weight loss, weakness, and fatigue. Because early-stage colorectal cancer often causes few or no symptoms, routine screening through colonoscopy or stool-based tests is critical. When detected early, colorectal cancer is highly treatable.

Standard treatments for colorectal cancer may involve surgery, chemotherapy, radiation therapy, targeted therapy, or a combination of these approaches. While these treatments can be lifesaving, they may also bring significant side effects. Nausea, vomiting, loss of appetite, chronic pain, neuropathy, anxiety, and sleep disturbances are common complaints among patients undergoing treatment.

This is where medical marijuana, also known as medical cannabis, has entered the conversation. In many states, colorectal cancer qualifies as a condition for medical marijuana use. Cannabis contains compounds called cannabinoids, including THC (tetrahydrocannabinol) and CBD (cannabidiol), which interact with the body’s endocannabinoid system. This system plays a role in regulating pain, mood, appetite, and inflammation. For colorectal cancer patients, medical marijuana may help manage chemotherapy-induced nausea and vomiting, which can be debilitating and lead to dehydration or malnutrition. Cannabis may also stimulate appetite in patients experiencing weight loss or cachexia, a condition marked by severe muscle wasting. Additionally, some patients report relief from cancer-related pain and improved sleep. Preliminary laboratory studies have also explored whether cannabinoids might have anti-tumor effects, including slowing cancer cell growth or promoting cancer cell death. However, these findings are largely based on preclinical research in cell cultures or animal models. Clinical evidence in humans remains limited, and medical marijuana should not be viewed as a substitute for standard cancer treatment. As with any medication, cannabis carries risks. Short-term side effects can include dizziness, dry mouth, impaired concentration, anxiety, and increased heart rate. In some individuals, particularly those predisposed to mental health conditions, high-THC products may worsen anxiety or trigger psychotic symptoms. Long-term or heavy use may lead to cannabis use disorder, characterized by dependence and difficulty controlling consumption. Overuse of marijuana, much like excessive alcohol consumption, can create health and social problems. Chronic heavy use has been associated with cognitive impairment, respiratory issues when smoked, and potential interactions with other medications. For cancer patients already managing complex treatment regimens, careful medical supervision is essential. Colorectal cancer patients considering medical marijuana should consult their oncologist or healthcare provider to discuss potential benefits, risks, and legal considerations in their state. When used responsibly and under medical guidance, cannabis may serve as a supportive tool in managing symptoms. But as with alcohol and many other substances, moderation and informed use are key to minimizing harm and maximizing potential benefit.

The Fresh Toast is a daily lifestyle platform with a side of cannabis. For more information, visit www.thefreshtoast.com.

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